DHM (dihydromyricetin)Feem ntau yog siv los ua cov khoom siv botanical multifunctional nyob rau hauv dej haus, nutraceutical formulations thiab cosmetic systems, raws li ib tug nroj tsuag -derived compound haum rau formulation stability, tsw system compatibility thiab rau functional positioning nyob rau hauv niaj hnub tsim khoom, vim nws cov ntsiab lus antioxidant.
DHM siv hauv cov dej haus ua haujlwm
DHM nyob rau hauv cov dej haus yog dav siv raws li ib tug solubilized los yog microencapsulated botanical muaj nyob rau tom ntej - tiam dej haus.
1. Npaj-rau- haus dej (RTD) tshuab
Txhawm rau kom ua tiav qhov zoo meej thiab ruaj khov hauv dej- dej qab zib, DHM tau muab tso rau hauv kev tsim nrog kev pab cuam solubilization lossis los ntawm kev tawg ntawm cov khoom ntawm qib nano.
Nws kuj yog feem ntau ua ke nrog botanicals (tshuaj yej polyphenols, citrus flavonoids) los tsim ntau yam - txheej flavors.
Thaum ua tiav zoo, DHM tuaj yeem siv los txhawb "ntxuav daim ntawv lo botanical positioning" rau cov qauv tsim, thaum tsis cuam tshuam rau saj.
2. Cov hmoov sib tov sib xyaw
Txau- cov cab kuj qhuav yog siv los txhim kho kev sib cais ntawm DHM hauv cov hmoov dej haus.
Flowability thiab kev tiv thaiv ntawm agglomeration yog qee zaum ua tiav los ntawm kev siv maltodextrin lossis kev noj haus fiber ntau matrices.
Thaum buffered, nws raug xaiv los siv rau hauv cov dej haus acidic (pH 3-5).
DHM Siv nyob rau hauv Nutraceutical thiab Khoom Siv Khoom Noj
Nyob rau hauv nutraceutical txoj kev loj hlob, DHM (dihydromyricetin) yog siv raws li ib tug standardized botanical muaj nyob rau hauv capsule, ntsiav tshuaj, thiab functional food formulations.
1. Capsule thiab ntsiav tshuaj formulations
DHM hmoov yog tov nrog microcrystalline cellulose thiab excipients kom tau cov compression zoo ib yam.
Cov ntsiab lus tsis sib xws thiab kev txo qis ntawm kev sib cais thaum lub sijhawm tsim khoom tau ua tiav siv cov txheej txheem granulation.
Nws nquag tsim nrog lwm cov botanicals rau ntau -botanical complexes nrog rau lwm cov nroj tsuag extracts uas muaj flavonoids los tsim ntau yam formulation profiles.
2. Cov khoom noj khoom haus sib xyaw ua ke
DHM tau ntxiv rau cov khoom noj txom ncauj, cov pos hniav, thiab cov khoom noj muaj protein ntau raws li cov nroj tsuag ntuj - muab cov khoom muaj nqis.
Kev xav txog kev ruaj ntseg ntawm cov cua sov yog qhov tseem ceeb heev, tshwj xeeb tshaj yog nyob rau hauv cov txheej txheem ci los yog extrusion.
Lub encapsulated DHMs yog nyiam los txo cov degradation thaum raug thermal.
3. Cov khoom xyaw standardization siv
DHM tuaj yeem siv los ua cov cim kev sib txuas kom paub tseeb tias cov khoom sib xws hauv cov txheej txheem rho tawm.
HPLC tau txheeb xyuas cov qib purity yog siv los lav cov qauv tsim tawm ntawm cov neeg tsim khoom.
DHM Siv rau hauv daim ntawv thov tshuaj pleev ib ce thiab kho tus kheej
DHM kuj tseem siv rau hauv cov tshuaj pleev ib ce vim nws sib haum nrog emulsions, gels, thiab dej-raws li systems.
1. Kev tu tawv nqaij emulsions
DHM tau muab tso rau hauv cov khoom xyaw botanical ua haujlwm ntawm cov roj-hauv- dej- raws li cov tshuaj hydrating thiab tshuaj pleev.
Nws muaj peev xwm khi zoo nrog cov humectants xws li glycerin thiab propanediol kom ua tau zoo dua kev ntxhib los mos.
Emulsion stabilizers pab ua kom siab -viscosity systems tsis sib xws.
2. Serum thiab gel tshuab
Nyob rau hauv lub teeb yuag serums, lub hom phiaj yog kom tau txais cov khoom mus rau hauv daim tawv nqaij sai thiab ua kom pom tseeb, uas yog tiav nrog DHM.
Nws tuaj yeem siv ua ke nrog cov tshuab uas muaj hyaluronic acid thiab polymeric gelling agents.
Xim thiab ruaj khov tuaj yeem khaws cia hauv kev khaws cia los ntawm kev siv qee cov tshuaj chelates.
3. Cov plaub hau thiab tawv taub hau formulations
DHM tuaj yeem muab ntxiv rau botanicals xws li tawm - ntawm cov tawv taub hau tonics thiab cov tshuaj kho mob.
Nws tsuas yog soluble hauv cov tshuab uas muaj cawv lossis cov kuab tshuaj.
Formulation Techniques thiab Solubility Optimization ntawm DHM
Kev siv tswv yim ntawm DHM (dihydromyricetin) nyob ntawm ntau yam ntawm kev tsim engineering vim nws txwv tsis pub solubility.
1. Particle loj txo
Cov txheej txheem micronization ua rau thaj tsam ntawm qhov chaw thiab yog li txhawb kev sib cais hauv cov tshuab aqueous.
Ib qho kev siv dav hlau milling yog kom tau txais kev faib tawm ntawm cov hmoov zoo.
Qhov me me me me, qhov zoo dua qhov saj hauv dej haus.
2. Encapsulation systems
Lipids yog siv rau encapsulation ntawm cov khoom nyob rau hauv dej haus los yog tshuaj pleev ib ce tshuab, pab txhawb dispersibility.
Los ntawm kev tsim cov complexes nrog cyclodextrins, aqueous compatibility ntawm cov khoom tuaj yeem txhim kho.
Cov tshuaj tsuag- txoj kev ziab kom qhuav yog paub zoo rau lawv qhov scalability.
3. Co-Solvent systems
Solubility ntawm DHM nyob rau hauv cov kua formulations tuaj yeem txhim kho los ntawm kev sib xyaw ntawm ethanol thiab dej los yog sib xyaw ntawm polyols.
Hom co- cov kuab tshuaj uas tau xaiv yuav vam khom rau cov khoom lag luam kawg thiab cov kev xav tau ntawm kev tswj hwm.
Cov yam ntxwv ruaj khov thiab kev txiav txim siab ntawm DHM Powder.
Kev nkag siab txog kev ruaj ntseg yog qhov tseem ceeb thaum siv DHM hauv cov qauv kev lag luam.
1. pH rhiab heev
DHM ua haujlwm zoo dua ntawm pH 4.5 txog 7.0.
Qee zaum, cov formulations tsis ruaj khov thiab tej zaum yuav hloov nrog lub sij hawm nyob rau hauv huab alkaline tej yam kev mob.
2. Kev raug cua sov
Kev ncaj ncees ntawm DHM tuaj yeem cuam tshuam los ntawm kev ua haujlwm siab -, tshwj xeeb tshaj yog nyob rau hauv kev siv hluav taws xob ncaj qha.
Encapsulated hom ntawv muaj kev tiv thaiv zoo dua rau kev ua, xws li pasteurization.
3. Teeb pom kev zoo thiab oxygen
Txhawm rau tiv thaiv oxidative degradation, DHM yuav tsum muab khaws cia rau hauv cov thawv ntim khoom opaque.
Muaj peev xwm siv cov kab mob antioxidant ua ib feem ntawm cov txheej txheem nyuaj los txhim kho cov txee ruaj khov.
4. Cia tej yam kev mob
Nws raug nquahu kom khaws cia rau hauv qhov chaw txias, qhuav, thiab lub teeb -dawb ib puag ncig.
Hmoov flowability tuaj yeem khaws cia rau hauv cov av noo los ntawm kev siv cov nqa khoom hygroscopic.
Xaus
Nws yog ntau yam khoom xyaw rau cov dej haus ua haujlwm, nutraceutical, thiab cov khoom siv tshuaj pleev ib ce, nrog rau nws cov txiaj ntsig tseem ceeb yog kev hloov pauv hauv kev tsim, kev ruaj ntseg thiab kev tsim cov tswv yim, thiab kev sib raug zoo nrog kev huv huv tam sim no - cov khoom tsim khoom. Cov txheej txheem kev ua haujlwm, uas suav nrog encapsulation, solubilization, thiab particle engineering, ua lub luag haujlwm tseem ceeb hauv nws cov kev siv tau zoo, ua kom muaj kev sib txuas ntawm DHM mus rau ntau qhov kawg - siv cov ntawv thov thaum tswj xyuas qhov xav tau kev ntxhib los mos, ruaj khov, thiab cov yam ntxwv ntawm kev hnov qab. Hauv cov ntsiab lus, DHM yog lub platform muaj ntau yam khoom siv uas tuaj yeem siv los ntawm cov neeg tsim khoom los tsim cov txheej txheem botanical tshiab hauv cov zaub mov, dej haus, thiab kev saib xyuas tus kheej.
Sentian Bio muab cov qauv dawb, OEM / ODM cov khoom lag luam customized, thiab kev txhawb nqa kev tshaj lij. Tiv tauj peb txhua lub sijhawm ntawmsales3@sentianbio.comlos yogNYEEM NTXIV!
FAQ
1. Dab tsi yog DHM siv rau hauv kev tsim dej haus?
DHM yog ua haujlwm raws li cov khoom xyaw botanical rau cov dej haus ua haujlwm nyob rau hauv daim ntawv ntawm DRG los yog hmoov dej haus, thiab qee zaum cov solubilization los yog dispersion ntawm DHM ntsiab nyob rau hauv cov formulations yog tsim nyog.
2. DHM siv li cas hauv cov tshuaj ntsiav thiab tshuaj ntsiav tshuaj?
DHM yog ua ke nrog excipients thiab yog granulated los yog ncaj qha compressed kom ntseeg tau tias txawm faib cov ntsiab lus nyob rau hauv nutraceuticals.
3. Cov kev sib tw hauv kev tsim dab tsi cuam tshuam rau kev siv DHM?
Kev txwv dej solubility, ua qhov kub thiab txias, thiab kev ruaj ntseg hauv cov kua system yog qhov nyuaj.
4. DHM ruaj khov li cas hauv cov tshuaj pleev ib ce?
Txhawm rau faib cov khoom sib xws hauv cov tshuaj pleev, cov tshuaj pleev, thiab cov gels, DHM tau ruaj khov los ntawm ntau yam emulsifiers, solubilizers, thiab encapsulation systems.
Cov ntaub ntawv
1. Li, X., et al. (2021). "Flavonoid-raws li cov ntsiab lus hauv kev tsim cov khoom xyaw ua haujlwm: kev tsim thiab kev xav txog kev ruaj ntseg." Food Chemistry, 352, 129299.
2. Zhang, Y., & Wang, J. (2022). "Kev nce qib hauv botanical extraction thiab encapsulation technologies rau kev siv nutraceutical." Phau ntawv Journal of Functional Foods, 89, 104950.
3. European Food Safety Authority (EFSA). (2023). "Kev taw qhia txog cov khoom xyaw botanical hauv cov khoom noj ntxiv thiab kev ntsuas kev nyab xeeb." EFSA Journal, 21(4), e07891.
4. Smith, R. et al. (2020). "Txaus-cov txheej txheem ziab thiab microencapsulation rau polyphenol stabilization hauv cov khoom noj." Trends in Food Science & Technology, 98, 45–58.