Alpha Cyclodextrin yog dab tsi?
Alpha-cyclodextrin yog cyclic hexasaccharide tsim los ntawm rau 1,4- txuas d-glucose units, tsim los ntawm cov hmoov txhuv nplej siab los ntawm kev hloov pauv enzymatic. Nws nta cov qauv molecular tshwj xeeb- sab nrauv hydrophilic thiab cov kab noj hniav hydrophobic- tso cai rau nws los thaiv cov tebchaw uas tsis yog-polar. Nws yog dav siv los ua cov fiber ntau soluble, stabilizer, thiab emulsifier hauv cov khoom noj thiab tshuaj lag luam.
Txhua Yam Koj Yuav Tsum Paub
alpha{0}}cyclodextrin siv rau dab tsi?
-Cyclodextrin, lub nplhaib qauv los ntawm 6 cov piam thaj, yog cov khoom noj muaj kuab lom, hauv EU daim ntawv thov kev noj qab haus huv yog siv tau tias alpha-CD txo cov piam thaj hauv cov ntshav tom qab noj mov thiab tuaj yeem ua raws li emulsifier.
Puas yog cyclodextrin muaj kev nyab xeeb rau tib neeg?
Concentrations mus txog 0.1% ntawm -, -, thiab -cyclodextrins raug suav hais tias muaj kev nyab xeeb.
Puas yog cyclodextrin nce ntshav qab zib?
Cov lus xaus. Txoj kev tshawb no qhia tau hais tias kev koom ua ke ntawm alpha-cyclodextrin nyob rau hauv cov hmoov txhuv nplej siab- cov zaub mov tuaj yeem txo nws cov kev cuam tshuam tom qab glycemic thiab insulinemic.
Dab tsi yog qhov ntuj tsim ntawm cyclodextrin?
Cyclodextrins (CDs) yog ib hom cyclic oligosaccharide muab los ntawm tej yam ntuj tso xws li qos yaj ywm, pob kws, pob kws, thiab cassava starches.
Cov ntsiab lus tseem ceeb:
Cyclodextrins yog tsim los ntawm cov hmoov txhuv nplej siab los ntawm kev ua ntawm ib qho enzyme, cyclodextrin glycosyltransferase (CDTGase; ED 2.4.1.19). Cov tshuaj synthesis tau tshaj tawm, 1 tab sis nws yog ib qho nyuaj heev rau kev lag luam ntawm cyclodextrins. Alpha-, beta- thiab gamma-cyclodextrins muaj 6, 7 thiab 8 (1 → 4)- txuas -D-glucopyranosyl units, raws li, thiab yog cov tshuaj cyclodextrins predominate tsim los ntawm cov enzyme. Delta- thiab nu{17}}cyclodextrins, uas feem ntau muaj 9 thiab 12 glucosyl units hauv lub nplhaib, tau raug cais tawm hauv qhov me me thiab cov yam ntxwv, 2,3 thiab cov pov thawj tau tshaj tawm rau cyclodextrins uas muaj txog li 16 glucosyl units hauv lub nplhaib.4 Vim yog qhov tseem ceeb ntawm {{224}}, -cyclodextrins, lawv yog cov cyclodextrins ntawm kev lag luam tam sim no.
Inclusion Complexes:Vim nws cov kab noj hniav hydrophobic, nws tsim cov complexes nrog me me lipophilic molecules, ua rau kev tiv thaiv ntawm flavors, stabilization ntawm cov xim, thiab solubilization ntawm cov vitamins.
Kev noj qab haus huv thiab khoom noj khoom haus:Feem ntau ua lag luam raws li kev noj haus fiber ntau, cov kev tshawb fawb qhia 𝛼-CD tuaj yeem pab txhim kho cov ntshav lipid profile (txo LDL cholesterol) thiab txhim kho cov tshuaj insulin.
Kev Siv Hluav Taws Xob:Nws ua raws li emulsifier hauv cov zaub mov, txo cov rog nqus thiab npog cov ntxhiab tsw lossis tsw qab.
Kev siv tshuaj:Siv los txhim kho bioavailability ntawm cov tshuaj los ntawm kev ua kom cov solubility ntawm hydrophobic active cov khoom xyaw.
ANALYTICAL RESULTS
| Cov khoom kuaj | Method / Ref. | Specification | Kev tshwm sim | Xaus |
|---|---|---|---|---|
| Kev txheeb xyuas | Hauv -house ID / daim ntawv thov | Alpha{0}}cyclodextrin (EC 3.2.1.19) | Ua raws | Hla |
| Qhov tshwm sim | Pom kev | Dawb rau tawm -dawb hmoov | Dawb hmoov | Hla |
| Kev ua enzyme | Cyclodextrinase assay / tus neeg muag khoom txoj kev | NLT 5,000 U/g | 5,200 U/g | Hla |
| Lub luag haujlwm Unit txhais | Tus neeg muab khoom siv -txhais chav tsev | Qhia xwb | U/g qhia | Hla |
| pH (1% tov) | pH ntsuas | 4.5 – 7.0 | 5.4 | Hla |
| Poob rau ziab | Gravimetric / USP 731 | Tsawg dua lossis sib npaug li 8.0% | 4.3% | Hla |
| Lead (Pb) | ICP-MS / ICP-OES | Tsawg dua lossis sib npaug li 5.0 mg / kg | 0.18 mg/kg | Hla |
| Arsenic (As) | ICP-MS / ICP-OES | Tsawg dua lossis sib npaug li 3.0 mg / kg | 0.09 mg/kg | Hla |
| Cadmium (Cd) | ICP-MS / ICP-OES | Tsawg dua lossis sib npaug li 0.5 mg / kg | < 0.05 mg/kg | Hla |
| Mercury (Hg) | ICP-MS / ICP-OES | Tsawg dua lossis sib npaug li 0.5 mg / kg | < 0.01 mg/kg | Hla |
| Tag Nrho Phaj suav | Phaj suav | Tsawg dua lossis sib npaug li 50,000 CFU / g | 2.0 × 10³ CFU/g | Hla |
| Coliforms | Phaj suav | Tsawg dua lossis sib npaug li 30 CFU / g | < 10 CFU/g | Hla |
| E. coli | Tsis Muaj Kev Xeem | Tsis zoo / 25g | Tsis Pom | Hla |
| Salmonella | Tsis Muaj Kev Xeem | Tsis zoo / 25g | Tsis Pom | Hla |
Txheej txheem ntau lawm
